It was her reunion with Allen in Annie Hall (1977) that earned that earned her an Academy Award and Golden Globe.

Keaton appeared in many box-office hits like Looking for Mr. Goodbar, Manhattan and 1981’s Reds, with Warren Beatty, her co-star and director, whom she fell for hard. “The first time I saw Warren was in Splendor in the Grass (1961). I mean, come on! He was, I mean, to die for. A Dream. I mean, Bonnie and Clyde? Come on,” she said in an interview with Variety. “And not only was he beautiful, gorgeous and sexy and captivating and mysterious and a great movie star but he was also an unbelievable producer and director, or is rather, is also an unbelievable director and producer. All of this is just so unique.”

Expanding her portfolio of work as she matured, the Baby Boom star then appeared as the mother in Father of the Bride (1991) with Steve Martin, Manhattan Murder Mystery–her first with Allen since Annie Hall–and in 2000 she played in The Godfather Part III as the divorced wife of the mafia boss.

In 2003, she starred in 2003’s Something’s Gotta Give, where her comedic prowess was recognized by the Academy with a nomination, and the film would be her first box office hit since 1996’s First Wives Club, with Bette Midler and Goldie Hawn.

A consummate professional, her co-stars rave about her performances. “She’s nothing if not fascinating, and working with her, she’s very unpredictable, which I like,” said Jack Nicholson, who co-starred with Keaton in Something’s Gotta Give. “She’s very disciplined about it all. She approaches a script sort of like a play in that she has the entire script memorized before you start doing the movie, which I don’t know any other actors doing that.”

Unlike her character in the film, who falls in love with much the older boyfriend (Nicholson) of her daughter, Keaton was quite fond of her much younger co-star, Keanu Reeves.